Our pipeline

Innovative Therapies Addressing Critical Unmet Needs

Our pipeline represents the forefront of antiviral innovation. Grounded in the discovery of RdRp Thumb-1 as a novel, conserved viral target, we are developing transformative, broad-spectrum therapies designed to combat some of the world’s most pressing infectious diseases. Our lead candidate, MDL-001, is a first-in-class, orally administered antiviral targeting multiple high-burden viral pathogens.

Through rigorous science, bold innovation, and a commitment to global health, we are building a portfolio of best-in-class therapies that have the potential to protect billions of lives.

Indication

SARS-CoV-2 (and VOCs)

VIRAL FAMILY

Coronaviridae

Therapeutic Class

Best-in-class

PATIENT POPULATION

760M

IND Enabling

Indication

SARS-CoV-2 (and VOCs)

VIRAL FAMILY

Coronaviridae

Therapeutic Class

Best-in-class

PATIENT POPULATION

760M

IND Enabling

INDICATION

SARS-CoV-2 (and VOCs)

VIRAL FAMILY

Coronaviridae

Therapeutic Class

Best-in-class

PATIENT POPULATION

760M

IND Enabling

Indication

Human Coronavirus A

VIRAL FAMILY

Coronaviridae

Therapeutic Class

Best-in-class

PATIENT POPULATION

2B

Preclinical POC

Indication

Human Coronavirus A

VIRAL FAMILY

Coronaviridae

Therapeutic Class

Best-in-class

PATIENT POPULATION

2B

Preclinical POC

INDICATION

Human Coronavirus A

VIRAL FAMILY

Coronaviridae

Therapeutic Class

Best-in-class

PATIENT POPULATION

2B

Preclinical POC

Indication

Human Coronavirus B

VIRAL FAMILY

Coronaviridae

Therapeutic Class

Best-in-class

PATIENT POPULATION

2B

Preclinical POC

Indication

Human Coronavirus B

VIRAL FAMILY

Coronaviridae

Therapeutic Class

Best-in-class

PATIENT POPULATION

2B

Preclinical POC

INDICATION

Human Coronavirus B

VIRAL FAMILY

Coronaviridae

Therapeutic Class

Best-in-class

PATIENT POPULATION

2B

Preclinical POC

Indication

Influenza A

VIRAL FAMILY

Orthomyxoviridae

Therapeutic Class

Best-in-class

PATIENT POPULATION

700M

Preclinical POC

Indication

Influenza A

VIRAL FAMILY

Orthomyxoviridae

Therapeutic Class

Best-in-class

PATIENT POPULATION

700M

Preclinical POC

INDICATION

Influenza A

VIRAL FAMILY

Orthomyxoviridae

Therapeutic Class

Best-in-class

PATIENT POPULATION

700M

Preclinical POC

Indication

Influenza B

VIRAL FAMILY

Orthomyxoviridae

Therapeutic Class

Best-in-class

PATIENT POPULATION

300M

Preclinical POC

Indication

Influenza B

VIRAL FAMILY

Orthomyxoviridae

Therapeutic Class

Best-in-class

PATIENT POPULATION

300M

Preclinical POC

INDICATION

Influenza B

VIRAL FAMILY

Orthomyxoviridae

Therapeutic Class

Best-in-class

PATIENT POPULATION

300M

Preclinical POC

Indication

Norovirus

VIRAL FAMILY

Caliciviridae

Therapeutic Class

First-in-class

PATIENT POPULATION

685M

Preclinical POC

Indication

Norovirus

VIRAL FAMILY

Caliciviridae

Therapeutic Class

First-in-class

PATIENT POPULATION

685M

Preclinical POC

INDICATION

Norovirus

VIRAL FAMILY

Caliciviridae

Therapeutic Class

First-in-class

PATIENT POPULATION

685M

Preclinical POC

Indication

Hepatitis C

VIRAL FAMILY

Flaviviridae

Therapeutic Class

Best-in-class

PATIENT POPULATION

58M

Preclinical POC

Indication

Hepatitis C

VIRAL FAMILY

Flaviviridae

Therapeutic Class

Best-in-class

PATIENT POPULATION

58M

Preclinical POC

INDICATION

Hepatitis C

VIRAL FAMILY

Flaviviridae

Therapeutic Class

Best-in-class

PATIENT POPULATION

58M

Preclinical POC

Additional Antiviral Programs

Additional Antiviral Programs

Additional Antiviral Programs

The next generation of antivirals

The next generation of antivirals

Our infectious disease program is building on the success of MDL-001 and developing the next generation of antivirals that have broader activity and demonstrate best-in-class antiviral characteristics.

Our infectious disease program is building on the success of MDL-001 and developing the next generation of antivirals that have broader activity and demonstrate best-in-class antiviral characteristics.

Development

12

New Chemical Entities

Validated in cellular models of disease, targeting RdRP Thumb-1
Development

12

New Chemical Entities

Validated in cellular models of disease, targeting RdRP Thumb-1
Development

12

New Chemical Entities

Validated in cellular models of disease, targeting RdRP Thumb-1

Revolutionizing Antiviral Treatment

learn more

Partnerships

Join Us in Advancing Antiviral Innovation

Our pipeline is built on the foundation of bold science and transformative potential. We welcome partnerships to accelerate the development and deployment of these life-saving therapies.

Science

Breaking New Ground in Viral Biology

Our revolutionary approach targets the cryptic Thumb-1 allosteric site of the viral RdRp. This unique mechanism exploits a critical vulnerability, halting viral replication at its core.